How are APOE4, changes in body weight, and longevity related? Insights from a causal mediation analysis
The ε4 allele of the APOE gene (APOE4) is known for its negative association with human longevity; however, the mechanism is unclear. APOE4 is also linked to changes in body weight, and the latter changes were associated with survival in some studies. Here, we explore the role of aging changes in we...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2024-03-01
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| coleção: | Frontiers in Aging |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fragi.2024.1359202/full |
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