Outer membrane vesicles-based nano-regulator for cancer immunotherapy by modulating neutrophils N1 polarization and hitchhiking delivery

Abstract Efficient eradication of cancer cells and enhanced tumor accumulation of drug via immune cells represent promising strategies for cancer treatment, yet they remain significant challenges. Inspired by neutrophils (NEs), we designed a novel nano-regulator (OMV@PCB NPs) to improve cancer thera...

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Principais autores:	Xiaoning Liu, Qun Niu, Haoxiang Yang, Tongyao Du, Yichen Liu, Hengqi Zhou, Shuqi Wang, Lingli Shen, Xuannian Wang, Gaiping Zhang, Hua He
格式:	Artigo
語言:	Inglês
出版:	BMC 2025-10-01
叢編:	Journal of Nanobiotechnology
主題:	Neutrophil polarization TGF-β inhibitor Outer membrane vesicles (OMVs) Hitchhiking delivery Cancer immunotherapy
在線閱讀:	https://doi.org/10.1186/s12951-025-03658-7
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