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Targeting Amyloidogenic Processing of APP in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of senile dementia, characterized by neurofibrillary tangle and amyloid plaque in brain pathology. Major efforts in AD drug were devoted to the interference with the production and accumulation of amyloid-β peptide (Aβ), which plays a causal role in t...

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Bibliografske podrobnosti
Principais autores: Jing Zhao, Xinyue Liu, Weiming Xia, Yingkai Zhang, Chunyu Wang
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020-08-01
Serija:Frontiers in Molecular Neuroscience
Teme:
Online dostop:https://www.frontiersin.org/article/10.3389/fnmol.2020.00137/full
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