Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Abstract Background Actinobacillus pleuropneumoniae (APP) is a Gram-negative bacterium that causes respiratory disease in pigs, resulting in significant economic losses and reduced animal welfare. In Sweden, the drug of choice for treatment of APP infections is benzylpenicillin. However, limited pha...

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Hauptverfasser:	Marie Sjölund, Thomas Rosendal, Per Wallgren, Märit Pringle, Ulf Bondesson, Björn Bengtsson, Carl Ekstrand
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-04-01
Schriftenreihe:	Acta Veterinaria Scandinavica
Schlagworte:	Antibiotic Antimicrobial treatment Pharmacokinetics Pleuropneumonia Porcine Respiratory disease
Online-Zugang:	https://doi.org/10.1186/s13028-025-00806-9
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