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Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Abstract Background Actinobacillus pleuropneumoniae (APP) is a Gram-negative bacterium that causes respiratory disease in pigs, resulting in significant economic losses and reduced animal welfare. In Sweden, the drug of choice for treatment of APP infections is benzylpenicillin. However, limited pha...

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Uloženo v:
Hlavní autoři: Marie Sjölund, Thomas Rosendal, Per Wallgren, Märit Pringle, Ulf Bondesson, Björn Bengtsson, Carl Ekstrand
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-04-01
Edice:Acta Veterinaria Scandinavica
Témata:
Antibiotic
Antimicrobial treatment
Pharmacokinetics
Pleuropneumonia
Porcine
Respiratory disease
On-line přístup:https://doi.org/10.1186/s13028-025-00806-9
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