Fusobacterium periodonticum BCT protein targeting glucose metabolism to promote the epithelial-mesenchymal transition of esophageal cancer cells by lactic acid

Abstract Background The cancer microbiota was considered the main risk factor for cancer progression. We had proved that Fusobacterium periodonticum (F.p) was higher abundance in Esophageal cancer(EC)tissues. Bioinformation analysis found that BCT was a key virulence protein of F.p. However, little...

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Autors principals:	Xinxin Guo, Ping Wan, Weitao Shen, Mingjun Sun, Zhenyan Peng, Yinghao Liao, Yang Huang, Ran Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-04-01
Col·lecció:	Journal of Translational Medicine
Matèries:	Fusobacterium periodonticum Esophageal cancer Glycolysi TLR4/Akt/HIF-1α EMT
Accés en línia:	https://doi.org/10.1186/s12967-024-05157-z
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