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Risk of high-grade infections in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a meta-analysis of randomized controlled trials

BackgroundAlthough anti-epidermal growth factor receptor (EGFR) monoclonal antibodies cetuximab and panitumumab are extensively used in metastatic colorectal cancer therapy, their association with the risk of high grade infections remains unclear.ObjectiveThe purpose of this study was to systematica...

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Principais autores: Xueliang Chen, Cui Liu, Hualin Liao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-03-01
Serier:Frontiers in Oncology
Fag:
anti-EGFR monoclonal antibodies
colorectal cancer
febrile neutropenia
high-grade infections
meta-analysis
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2026.1783342/full
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