Fibrillarin-mediated ribosomal RNA maturation is a novel therapeutic vulnerability in triple-negative breast cancer

Abstract Background Triple-negative breast cancer (TNBC) remains one of the most challenging breast cancer subtypes to treat due to the lack of effective therapeutic options. Ribosome biogenesis has recently emerged as a promising therapeutic target across various cancers. Despite the current target...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Camille Jouines, Piero Lo Monaco, Angéline Gaucherot, Julie Radermecker, Caroline Isaac, Fleur Bourdelais, Marie-Ambre Monet, Marion Meyer, Mounira Chalabi-Dchar, Flora Nguyen Van Long, Laury Baillon, Carine Froment, Julien Marcoux, Christophe Vanbelle, Tanguy Fenouil, Sébastien Durand, Stéphane Giraud, Jean-Jacques Diaz, Virginie Marcel, Frédéric Catez
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2025-11-01
سلاسل:	Breast Cancer Research
الموضوعات:	Ribosome biogenesis rRNA maturation Fibrillarin Breast cancer Therapeutic target
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13058-025-02163-x
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!