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Assessment of the therapeutic potential of Hsp70 activator against prion diseases using in vitro and in vivo models

IntroductionPrion diseases are deadly neurodegenerative disorders in both animals and humans, causing the destruction of neural tissue and inducing behavioral manifestations. Heat shock proteins (Hsps), act as molecular chaperones by supporting the appropriate folding of proteins and eliminating the...

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Autori principali: Mohammed Zayed, Yong-Chan Kim, Byung-Hoon Jeong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-07-01
Serie:Frontiers in Cell and Developmental Biology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fcell.2024.1411529/full
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