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Assessment of the therapeutic potential of Hsp70 activator against prion diseases using in vitro and in vivo models

IntroductionPrion diseases are deadly neurodegenerative disorders in both animals and humans, causing the destruction of neural tissue and inducing behavioral manifestations. Heat shock proteins (Hsps), act as molecular chaperones by supporting the appropriate folding of proteins and eliminating the...

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Hlavní autoři: Mohammed Zayed, Yong-Chan Kim, Byung-Hoon Jeong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-07-01
Edice:Frontiers in Cell and Developmental Biology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fcell.2024.1411529/full
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