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The transcription factor FOXL2 mobilizes estrogen signaling to maintain the identity of ovarian granulosa cells

FOXL2 is a lineage determining transcription factor in the ovary, but its direct targets and modes of action are not fully characterized. In this study, we explore the targets of FOXL2 and five nuclear receptors in murine primary follicular cells. We found that FOXL2 is required for normal gene regu...

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Autori principali: Adrien Georges, David L'Hôte, Anne Laure Todeschini, Aurélie Auguste, Bérangère Legois, Alain Zider, Reiner A Veitia
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2014-11-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/04207
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