Suppressing Cdk5 Activity by Luteolin Inhibits MPP⁺-Induced Apoptotic of Neuroblastoma through Erk/Drp1 and Fak/Akt/GSK3β Pathways

Parkinson’s disease (PD) is characterized by the progressive degeneration of dopaminergic neurons. The cause of PD is still unclear. Oxidative stress and mitochondrial dysfunction have been linked to the development of PD. Luteolin, a non-toxic flavonoid, has become interested in an alternative medi...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ratchaneekorn Reudhabibadh, Thunwa Binlateh, Pennapa Chonpathompikunlert, Nongyao Nonpanya, Peerada Prommeenate, Pithi Chanvorachote, Pilaiwanwadee Hutamekalin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-02-01
Schriftenreihe:	Molecules
Schlagworte:	1-methyl-4-phenylpyridinium ion apoptosis Cdk5 luteolin oxidative stress Parkinson’s disease
Online-Zugang:	https://www.mdpi.com/1420-3049/26/5/1307
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