β2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune Encephalomyelitis

Heterodimeric β2 integrin surface receptors (CD11a-d/CD18) are specifically expressed by leukocytes that contribute to pathogen uptake, cell migration, immunological synapse formation and cell signaling. In humans, the loss of CD18 expression results in leukocyte adhesion deficiency syndrome (LAD-)1...

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Hlavní autoři:	Monika Bednarczyk, Vanessa Bolduan, Maximilian Haist, Henner Stege, Christoph Hieber, Lisa Johann, Carsten Schelmbauer, Michaela Blanfeld, Khalad Karram, Jenny Schunke, Tanja Klaus, Ingrid Tubbe, Evelyn Montermann, Nadine Röhrig, Maike Hartmann, Jana Schlosser, Tobias Bopp, Björn E Clausen, Ari Waisman, Matthias Bros, Stephan Grabbe
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-07-01
Edice:	Cells
Témata:	β2 integrins dendritic cells cytokine signal transducers and activators of transcription suppressor of cytokines experimental autoimmune encephalomyelitis
On-line přístup:	https://www.mdpi.com/2073-4409/11/14/2188
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