β2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune Encephalomyelitis

Heterodimeric β2 integrin surface receptors (CD11a-d/CD18) are specifically expressed by leukocytes that contribute to pathogen uptake, cell migration, immunological synapse formation and cell signaling. In humans, the loss of CD18 expression results in leukocyte adhesion deficiency syndrome (LAD-)1...

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主要な著者:	Monika Bednarczyk, Vanessa Bolduan, Maximilian Haist, Henner Stege, Christoph Hieber, Lisa Johann, Carsten Schelmbauer, Michaela Blanfeld, Khalad Karram, Jenny Schunke, Tanja Klaus, Ingrid Tubbe, Evelyn Montermann, Nadine Röhrig, Maike Hartmann, Jana Schlosser, Tobias Bopp, Björn E Clausen, Ari Waisman, Matthias Bros, Stephan Grabbe
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2022-07-01
シリーズ:	Cells
主題:	β2 integrins dendritic cells cytokine signal transducers and activators of transcription suppressor of cytokines experimental autoimmune encephalomyelitis
オンライン･アクセス:	https://www.mdpi.com/2073-4409/11/14/2188
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