The causal impact of bioavailable testosterone levels on osteoarthritis: a bidirectional Mendelian randomized study

Abstract Background It has been shown that low testosterone levels are associated with the development of osteoarthritis (OA). In our study, we aimed to investigate a bidirectional causal relationship between bioavailable testosterone levels and OA using Mendelian randomization (MR) analysis. Method...

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Detalhes bibliográficos

Principais autores:	Zong Jiang, Xiaoling Yao, Yuzheng Yang, Fang Tang, Wukai Ma, Xueming Yao, Weiya Lan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-04-01
coleção:	BMC Musculoskeletal Disorders
Assuntos:	Bioavailable testosterone levels Osteoarthritis Mendelian randomization Bidirectional
Acesso em linha:	https://doi.org/10.1186/s12891-025-08626-8
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