Integrated Lymphopenia Analysis in Younger and Older Patients With Multiple Sclerosis Treated With Cladribine Tablets

Cladribine tablets (CladT) preferentially reduce B and T lymphocyte levels. As aging is associated with a decline in immune function, the effect of CladT on lymphocyte levels may differ by age. This post hoc analysis combined data from the Phase 3 CLARITY, CLARITY Extension, and ORACLE-MS studies to...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Gavin Giovannoni, Patricia K. Coyle, Patrick Vermersch, Bryan Walker, Julie Aldridge, Axel Nolting, Andrew Galazka, Caroline Lemieux, Thomas P. Leist
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-12-01
Edice:	Frontiers in Immunology
Témata:	cladribine tablets lymphocyte subsets lymphopenia multiple sclerosis age
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.763433/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!