Enriched Environment Suppresses Neuronal Ferroptosis Through SIRT1/AKT/GSK3β-Dependent Glycogen Metabolic Reprogramming After Cerebral Ischemia–Reperfusion

Neuronal ferroptosis is a key contributor to secondary brain injury following cerebral ischemia, yet the metabolic mechanisms governing this process remain poorly understood. Enriched environment (EE) is a housing paradigm that provides enhanced sensory, cognitive, and social stimulation through com...

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Detalhes bibliográficos

Principais autores:	Bao Zhou, Yixi Hao, Pengkun Yang, Haocheng Qin, Zheng Zhang, Na Ren, Lu Sun, Zhengran Ding, Zhong He, Shuai Zhang, Zijian Hua, Ya Zheng, Ce Li, Shenyi Kuang, Yulian Zhu, Kewei Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-04-01
coleção:	Antioxidants
Assuntos:	cerebral ischemia-reperfusion injury glycogen metabolic reprogramming oxidative stress ferroptosis enriched environment
Acesso em linha:	https://www.mdpi.com/2076-3921/15/5/570
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