Rapamycin Enhances Mitophagy and Attenuates Apoptosis After Spinal Ischemia-Reperfusion Injury

The spinal cord is extremely vulnerable to ischemia-reperfusion (I/R) injury, and the mitochondrion is the most crucial interventional target. Rapamycin can promote autophagy and exert neuroprotective effects in several diseases of the central nervous system. However, the impact of rapamycin via mod...

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Detalles Bibliográficos

Principais autores:	Qiang Li, Shane Gao, Zhanrong Kang, Meiyan Zhang, Xin Zhao, Yu Zhai, Jianming Huang, Guo-Yuan Yang, Wanju Sun, Jian Wang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2018-12-01
Series:	Frontiers in Neuroscience
Assuntos:	apoptosis mitophagy ischemia-reperfusion injury rapamycin spinal cord
Acceso en liña:	https://www.frontiersin.org/article/10.3389/fnins.2018.00865/full
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