Adoptive Transfer of Immune Cells Into RAG2IL-2Rγ-Deficient Mice During Litomosoides sigmodontis Infection: A Novel Approach to Investigate Filarial-Specific Immune Responses

Despite long-term mass drug administration programmes, approximately 220 million people are still infected with filariae in endemic regions. Several research studies have characterized host immune responses but a major obstacle for research on human filariae has been the inability to obtain adult wo...

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Main Authors:	Anna Wiszniewsky, Laura E. Layland, Kathrin Arndts, Lisa M. Wadephul, Ruth S. E. Tamadaho, Dennis Borrero-Wolff, Valerine C. Chunda, Chi Anizette Kien, Achim Hoerauf, Samuel Wanji, Manuel Ritter
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2021-11-01
Series:	Frontiers in Immunology
Subjects:	Filariae Litomosoides sigmodontis CD4+ and CD8+ T cells adoptive transfer anti-filarial immunity Th17 polarization
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.777860/full
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