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miR-1226-5p is involved in radioresistance of colorectal cancer by activating M2 macrophages through suppressing IRF1

Abstract Background Although the representative treatment for colorectal cancer (CRC) is radiotherapy, cancer cells survive due to inherent radioresistance or resistance acquired after radiation treatment, accelerating tumor malignancy and causing local recurrence and metastasis. However, the detail...

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Principais autores: Jae Yeon Choi, Hyun Jeong Seok, Dong Hyeon Lee, Junhye Kwon, Ui Sup Shin, Incheol Shin, In Hwa Bae
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-10-01
coleção:Journal of Translational Medicine
Assuntos:
Radioresistance of colorectal cancer
miR-1226-5p
circSLC43A1
IRF1
M2 macrophage
Tumor malignancy
Acesso em linha:https://doi.org/10.1186/s12967-024-05797-1
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