miR-1226-5p is involved in radioresistance of colorectal cancer by activating M2 macrophages through suppressing IRF1

Abstract Background Although the representative treatment for colorectal cancer (CRC) is radiotherapy, cancer cells survive due to inherent radioresistance or resistance acquired after radiation treatment, accelerating tumor malignancy and causing local recurrence and metastasis. However, the detail...

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Bibliographic Details

Main Authors:	Jae Yeon Choi, Hyun Jeong Seok, Dong Hyeon Lee, Junhye Kwon, Ui Sup Shin, Incheol Shin, In Hwa Bae
Format:	Artigo
Language:	Inglês
Published:	BMC 2024-10-01
Series:	Journal of Translational Medicine
Subjects:	Radioresistance of colorectal cancer miR-1226-5p circSLC43A1 IRF1 M2 macrophage Tumor malignancy
Online Access:	https://doi.org/10.1186/s12967-024-05797-1
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