The <i>Trypanosoma cruzi</i> TcrNT2 Nucleoside Transporter Is a Conduit for the Uptake of 5-F-2′-Deoxyuridine and Tubercidin Analogues

Among the scarce validated drug targets against Chagas disease (CD), caused by <i>Trypanosoma cruzi</i>, the parasite’s nucleoside salvage system has recently attracted considerable attention. Although the trypanocidal activity of tubercidin (7-deazapurine) has long been known, the identification of...

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Hlavní autoři:	Mustafa M. Aldfer, Ibrahim A. Alfayez, Hamza A. A. Elati, Nilanjana Gayen, Ehab Kotb Elmahallawy, Ana Milena Murillo, Sabrina Marsiccobetre, Serge Van Calenbergh, Ariel M. Silber, Harry P. de Koning
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-11-01
Edice:	Molecules
Témata:	<i>Trypanosoma cruzi</i> nucleoside transporter pyrimidine transporter thymidine TcrNT2 tubercidin analog
On-line přístup:	https://www.mdpi.com/1420-3049/27/22/8045
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