The <i>Trypanosoma cruzi</i> TcrNT2 Nucleoside Transporter Is a Conduit for the Uptake of 5-F-2′-Deoxyuridine and Tubercidin Analogues

Among the scarce validated drug targets against Chagas disease (CD), caused by <i>Trypanosoma cruzi</i>, the parasite’s nucleoside salvage system has recently attracted considerable attention. Although the trypanocidal activity of tubercidin (7-deazapurine) has long been known, the identification of...

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Detalhes bibliográficos

Principais autores:	Mustafa M. Aldfer, Ibrahim A. Alfayez, Hamza A. A. Elati, Nilanjana Gayen, Ehab Kotb Elmahallawy, Ana Milena Murillo, Sabrina Marsiccobetre, Serge Van Calenbergh, Ariel M. Silber, Harry P. de Koning
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-11-01
coleção:	Molecules
Assuntos:	<i>Trypanosoma cruzi</i> nucleoside transporter pyrimidine transporter thymidine TcrNT2 tubercidin analog
Acesso em linha:	https://www.mdpi.com/1420-3049/27/22/8045
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