DEPTOR Deficiency-Mediated mTORc1 Hyperactivation in Vascular Endothelial Cells Promotes Angiogenesis

Background/Aims: The mechanistic target of rapamycin (mTOR) signaling pathway is essential for angiogenesis and embryonic development. DEP domain-containing mTOR-interacting protein (DEPTOR) is an mTOR binding protein that functions to inhibit the mTOR pathway In vitro experiments suggest that DEPTO...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Yan Ding, Lanlan Shan, Wenqing Nai, Xiaojun Lin, Ling Zhou, Xiaoying Dong, Hongyuan Wu, Min Xiao, Xuejuan Zhou, Linlin Wang, Ting Li, You Fu, Yijun Lin, Chunhong Jia, Meng Dai, Xiaochun Bai
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Cell Physiol Biochem Press GmbH & Co KG 2018-03-01
Edice:	Cellular Physiology and Biochemistry
Témata:	Angiogenesis DEPTOR mTORC1 Vascular endothelial cell VEGF HIF-1α
On-line přístup:	https://www.karger.com/Article/FullText/488619
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!