Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-β1/Smad3 and Wnt/β-Catenin Signaling Pathways

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by fibroblast proliferation and extracellular matrix remodeling; however, the molecular mechanisms underlying its occurrence and development are not yet fully understood. Despite it having a variety of beneficial pharmacologic...

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Detalhes bibliográficos

Principais autores:	Fan Yang, Zhen-feng Hou, Hao-yue Zhu, Xiao-xuan Chen, Wan-yang Li, Ren-shuang Cao, Yu-xuan Li, Ru Chen, Wei Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-01-01
coleção:	Frontiers in Pharmacology
Assuntos:	catalpol idiopathic pulmonary fibrosis epithelial-mesenchymal transition Smad3 Wnt3a
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2020.594139/full
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