CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism
Abstract Background Fibrogenesis is a common pathological feature of endometriotic lesions and contributes to the development of endometriosis-associated chronic pelvic pain and infertility. TGF-β is a critical factor in the induction of fibrogenesis; however, the underlying regulatory mechanisms of...
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| Huvudupphov: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
BMC
2025-07-01
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| Serie: | Journal of Translational Medicine |
| Ämnen: | |
| Länkar: | https://doi.org/10.1186/s12967-025-06804-9 |
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