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5-Azacytidine restores interleukin 6-increased production in mesenchymal stromal cells from myelodysplastic patients

Introduction: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematological diseases. In addition to defects in hematologic progenitor and stem cells, dysfunctions in the bone marrow microenvironment (BMM) participate in the MDS pathogenesis. Furthermore, the immune response is d...

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Principais autores: Matilde Boada, Lourdes Echarte, Cecilia Guillermo, Lilián Diaz, Cristina Touriño, Sofía Grille
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021-01-01
Series:Hematology, Transfusion and Cell Therapy
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2531137920300043
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