The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches

APOBEC3 family DNA cytosine deaminases provide overlapping defenses against pathogen infections. However, most viruses have elaborate evasion mechanisms such as the HIV-1 Vif protein, which subverts cellular CBF-β and a polyubiquitin ligase complex to neutralize these enzymes. Despite advances in AP...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Christopher Richards, John S. Albin, Özlem Demir, Nadine M. Shaban, Elizabeth M. Luengas, Allison M. Land, Brett D. Anderson, John R. Holten, John S. Anderson, Daniel A. Harki, Rommie E. Amaro, Reuben S. Harris
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2015-12-01
Serie:	Cell Reports
Soggetti:	APOBEC3F HIV-1 pathogen-host interaction Vif APOBEC3F-Vif interface
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124715012565
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!