Mesencephalic Astrocyte‐Derived Neurotrophic Factor Binds BAX to Preserve Mitochondrial Homeostasis and Energy Metabolism for Relieving Myocardial Hypertrophy

Abstract Myocardial hypertrophy (MH) is a heart disease accompanied by mitochondrial energy disorder and oxidative stress for cardiomyocyte apoptosis. Mesencephalic astrocyte‐derived neurotrophic factor (MANF), with anti‐inflammation and cytoprotection, is found to be negatively correlated with atri...

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Principais autores:	Dong Wang, Xinru Zhang, Baolong Wang, Haipeng Li, Dongshuo Xu, Yun Yang, Jialu Zhang, Wenbing Wang, Ren Zhang, Xinyu Wang, Yunfeng Cai, Shiyu Cao, Chao Hou, Changhui Wang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2025-10-01
Series:	Advanced Science
Assuntos:	Bcl2‐associated X protein cytochrome c mesencephalic astrocyte‐derived neurotrophic factor mitochondria myocardial hypertrophy
Acceso en liña:	https://doi.org/10.1002/advs.202502835
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