Interneurons secrete prosaposin, a neurotrophic factor, to attenuate kainic acid-induced neurotoxicity

Prosaposin (PS) is a secretory neurotrophic factor, as well as a regulator of lysosomal enzymes. We previously reported the up-regulation of PS and the possibility of its axonal transport by GABAergic interneurons after exocitotoxicity induced by kainic acid (KA), a glutamate analog. In the present...

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Detalhes bibliográficos

Principais autores:	Hiroaki Nabeka, Shouichiro Saito, Xuan Li, Tetsuya Shimokawa, Md. Sakirul Islam Khan, Kimiko Yamamiya, Soichiro Kawabe, Takuya Doihara, Fumihiko Hamada, Naoto Kobayashi, Seiji Matsuda
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2017-12-01
coleção:	IBRO Reports
Assuntos:	Interneurons transport Neurotrophic factor Neuroprotection Prosaposin Kainic acid
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2451830117300201
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