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Expression of prosaposin and its receptors in the rat cerebellum after kainic acid injection

Prosaposin (PSAP), a highly conserved glycoprotein, is a precursor of saposins A–D. Accumulating evidence suggests that PSAP is a neurotrophic factor that induces differentiation and prevents death in a variety of neuronal cells through the active region within the saposin C domain both in vivo and...

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Principais autores: Xuan Li, Hiroaki Nabeka, Shouichiro Saito, Tetsuya Shimokawa, Md. Sakirul Islam Khan, Kimiko Yamamiya, Fengping Shan, Huiling Gao, Cheng Li, Seiji Matsuda
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017-06-01
Serier:IBRO Reports
Fag:
Prosaposin
GPR37
GPR37L1
Kainic acid
Cerebellum
Neurodegeneration
Online adgang:http://www.sciencedirect.com/science/article/pii/S2451830116300280
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