Predictive value of the maternal alpha-fetoprotein variant, L2, during the first trimester of pregnancy screening for fetal trisomy 21, trisomy 18, and neural tube defects

Abstract Background To assess the predictive usefulness of maternal serum alpha fetoprotein variant L2 (AFP-L2) for fetal trisomy 21, trisomy 18, and neural tube abnormalities (NTDs) in early pregnancy screening. Methods This retrospective case-control study including 155 fetuses diagnosed with tris...

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मुख्य लेखकों:	Yiming Chen, Wenwen Ning, Caihe Wen, Linyuan Gu, Xuelian Chu
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2025-08-01
श्रृंखला:	BMC Pregnancy and Childbirth
विषय:	Early pregnancy Prenatal screening Alpha-fetoprotein variant L2 Trisomy 21 Trisomy 18 Neural tube defects
ऑनलाइन पहुंच:	https://doi.org/10.1186/s12884-025-07893-6
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