Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes

Legionella pneumophila extensively modulates the host ubiquitin network to create the Legionella-containing vacuole (LCV) for its replication. Many of its virulence factors function as ubiquitin ligases or deubiquitinases (DUBs). Here, we identify Lem27 as a DUB that displays a preference for diubiq...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Shuxin Liu, Jiwei Luo, Xiangkai Zhen, Jiazhang Qiu, Songying Ouyang, Zhao-Qing Luo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	eLife Sciences Publications Ltd 2020-11-01
Schriftenreihe:	eLife
Schlagworte:	Legionella pneumophila type iv secretion bacterial virulence otu deubiquitinase
Online-Zugang:	https://elifesciences.org/articles/58114
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