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Crystal structure of a natural light-gated anion channelrhodopsin

The anion channelrhodopsin GtACR1 from the alga Guillardia theta is a potent neuron-inhibiting optogenetics tool. Presented here, its X-ray structure at 2.9 Å reveals a tunnel traversing the protein from its extracellular surface to a large cytoplasmic cavity. The tunnel is lined primarily by small...

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Autors principals: Hai Li, Chia-Ying Huang, Elena G Govorunova, Christopher T Schafer, Oleg A Sineshchekov, Meitian Wang, Lei Zheng, John L Spudich
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2019-01-01
Col·lecció:eLife
Matèries:
Accés en línia:https://elifesciences.org/articles/41741
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