Stimulation of DNA Glycosylase Activities by XPC Protein Complex: Roles of Protein-Protein Interactions
We showed that XPC complex, which is a DNA damage detector for nucleotide excision repair, stimulates activity of thymine DNA glycosylase (TDG) that initiates base excision repair. XPC appeared to facilitate the enzymatic turnover of TDG by promoting displacement from its own product abasic site, a...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley
2010-01-01
|
| Schriftenreihe: | Journal of Nucleic Acids |
| Online-Zugang: | http://dx.doi.org/10.4061/2010/805698 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|