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High contiguity de novo genome assembly and DNA modification analyses for the fungus fly, Sciara coprophila, using single-molecule sequencing

Abstract Background The lower Dipteran fungus fly, Sciara coprophila, has many unique biological features that challenge the rule of genome DNA constancy. For example, Sciara undergoes paternal chromosome elimination and maternal X chromosome nondisjunction during spermatogenesis, paternal X elimina...

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Principais autores: John M. Urban, Michael S. Foulk, Jacob E. Bliss, C. Michelle Coleman, Nanyan Lu, Reza Mazloom, Susan J. Brown, Allan C. Spradling, Susan A. Gerbi
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2021-09-01
סדרה:BMC Genomics
נושאים:
Genome assembly
Single molecule sequencing
Long reads
Optical maps
DNA modifications
Emerging model organism
גישה מקוונת:https://doi.org/10.1186/s12864-021-07926-2
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