High contiguity de novo genome assembly and DNA modification analyses for the fungus fly, Sciara coprophila, using single-molecule sequencing

Abstract Background The lower Dipteran fungus fly, Sciara coprophila, has many unique biological features that challenge the rule of genome DNA constancy. For example, Sciara undergoes paternal chromosome elimination and maternal X chromosome nondisjunction during spermatogenesis, paternal X elimina...

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Autori principali:	John M. Urban, Michael S. Foulk, Jacob E. Bliss, C. Michelle Coleman, Nanyan Lu, Reza Mazloom, Susan J. Brown, Allan C. Spradling, Susan A. Gerbi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2021-09-01
Serie:	BMC Genomics
Soggetti:	Genome assembly Single molecule sequencing Long reads Optical maps DNA modifications Emerging model organism
Accesso online:	https://doi.org/10.1186/s12864-021-07926-2
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