Development and Validation of HPLC-DAD Method for the Determination of Favipiravir and Studying the Impact of Vitamin C on the Pharmacokinetics of COVID-19 Antiviral Drug Favipiravir

A novel, sensitive, and low-cost HPLC method for the rapid determination of favipiravir (FVR) in rat plasma was developed and validated, and the effect of vitamin C on FVR pharmacokinetic parameters was investigated. FVR and oxcarbazepine (IS) were separated using a mobile phase of 50% acetonitrile...

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Ngā kaituhi matua:	Mohammad Hailat, Israa Al-Ani, Zainab Zakareia, Ramadan Al-Shdefat, Osaid Al-Meanazel, Md. Khalid Anwer, Mohammed Hamad, Walid Abu Rayyan, Riad Awad, Wael Abu Dayyih
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2022-10-01
Rangatū:	Separations
Ngā marau:	favipiravir vitamin C HPLC validation plasma pharmacokinetics
Urunga tuihono:	https://www.mdpi.com/2297-8739/9/10/303
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!