Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies

Bisoprolol hemifumarate (BH) is an antihypertensive drug that is used as first-line treatment for chronic hypertension and angina pectoris. Our study was performed to enhance the transdermal delivery of BH, a hydrophilic drug active with high molecular weight, through differently prepared hydrogels....

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Principais autores:	Mahmoud H. Teaima, Mohamed Azmi Ahmed Mohamed, Randa Tag Abd El Rehem, Saadia A. Tayel, Mohamed A. El-Nabarawi, Shahinaze A. Fouad
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-05-01
Serija:	Pharmaceutics
Teme:	bisoprolol hemifumarate (BH) hypertension hydrogels ex vivo permeation permeation enhancers rat skin
Online dostop:	https://www.mdpi.com/1999-4923/13/5/682
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