Design, optimization and characterization of mucoadhesive buccal film as a novel delivery system for doxazosin mesylate
Abstract Doxazosin mesylate is a selective α1-adrenergic receptor antagonist with low oral bioavailability due to poor aqueous solubility and extensive first-pass hepatic metabolism. This study aimed to design and optimize a doxazosin mucoadhesive buccal film to overcome hepatic metabolism and enabl...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer
2026-06-01
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| coleção: | Saudi Pharmaceutical Journal |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/s44446-026-00087-x |
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