Efficient production of a cyclic dipeptide (cyclo-TA) using heterologous expression system of filamentous fungus Aspergillus oryzae

Abstract Background Cyclic dipeptides are an important class of natural products owing to their structural diversity and biological activities. In fungi, the cyclo-ring system is formed through the condensation of two α-amino acids via non-ribosomal peptide synthetase (NRPS). However, there are few...

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Autors principals:	Jianzhao Qi, Haiyan Han, Dan Sui, Shengnan Tan, Changli Liu, Pengchao Wang, Chunliang Xie, Xuekui Xia, Jin-ming Gao, Chengwei Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-07-01
Col·lecció:	Microbial Cell Factories
Matèries:	Aspergillus oryzae Cyclic dipeptide Echinulin Heterologous expression NRPS
Accés en línia:	https://doi.org/10.1186/s12934-022-01872-8
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