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Enhanced Bacitracin Production by Systematically Engineering S-Adenosylmethionine Supply Modules in Bacillus licheniformis

Bacitracin is a broad-spectrum veterinary antibiotic that widely used in the fields of veterinary drug and feed additive. S-Adenosylmethionine (SAM) is a critical factor involved in many biochemical reactions, especially antibiotic production. However, whether SAM affects bacitracin synthesis is sti...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Dongbo Cai, Bowen Zhang, Jiang Zhu, Haixia Xu, Pei Liu, Zhi Wang, Junhui Li, Zhifan Yang, Xin Ma, Shouwen Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-04-01
Schriftenreihe:Frontiers in Bioengineering and Biotechnology
Schlagworte:
bacitracin
S-Adenosylmethionine
Bacillus licheniformis
methionine
metabolic engineering
Online-Zugang:https://www.frontiersin.org/article/10.3389/fbioe.2020.00305/full
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