Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency
Lysine (K) type cationic lipid with a propyl spacer and ditetradecyl hydrophobic moieties composing liposomes, K3C14, previously studied for gene delivery, were reported to activate the NLRP3 inflammasomes in human macrophages via the conventional phagolysosomal pathway. In this study, K3C16, a prop...
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| Автори: | , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2019-07-01
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| Серія: | Biochemistry and Biophysics Reports |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S240558081830311X |
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