Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency

Lysine (K) type cationic lipid with a propyl spacer and ditetradecyl hydrophobic moieties composing liposomes, K3C14, previously studied for gene delivery, were reported to activate the NLRP3 inflammasomes in human macrophages via the conventional phagolysosomal pathway. In this study, K3C16, a prop...

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Hlavní autoři:	Jieyan He, Tianshu Li, Tomasz Próchnicki, Gabor Horvath, Eicke Latz, Shinji Takeoka
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2019-07-01
Edice:	Biochemistry and Biophysics Reports
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S240558081830311X
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