Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

ABSTRACT Immune checkpoint inhibitors (ICIs) have transformed cancer therapy by targeting crucial coinhibitory pathways. Pathways involving PD‐1/PD‐L1 and CTLA‐4 are essential for immune homeostasis but are frequently exploited by tumors to evade immune surveillance. ICIs block these interactions, u...

Descrición completa

Detalles Bibliográficos

Principais autores:	Qintao Ge, Liu Yu, Jiahe Lu, Aihetaimujiang Anwaier, Xiyue Xiao, Yonghao Chen, Dingwei Ye, Hailiang Zhang, Wenhao Xu, Wenbin Dai
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2026-06-01
Series:	MedComm
Assuntos:	immune checkpoints immune combination therapies immune escape immune resistance immunotherapy tumor microenvironment
Acceso en liña:	https://doi.org/10.1002/mco2.70771
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!