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The chemerin/CMKLR1 axis regulates intestinal graft-versus-host disease

Gastrointestinal graft-versus-host disease (GvHD) is a major cause of mortality and morbidity following allogeneic bone marrow transplantation (allo-BMT). Chemerin is a chemotactic protein that recruits leukocytes to inflamed tissues by interacting with ChemR23/CMKLR1, a chemotactic receptor express...

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Principais autores: Erica Dander, Paola Vinci, Stefania Vetrano, Camilla Recordati, Rocco Piazza, Grazia Fazio, Donatella Bardelli, Mattia Bugatti, Francesca Sozio, Andrea Piontini, Sonia Bonanomi, Luca Bertola, Elena Tassistro, Maria Grazia Valsecchi, Stefano Calza, William Vermi, Andrea Biondi, Annalisa Del Prete, Silvano Sozzani, Giovanna D’Amico
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2023-03-01
Serier:JCI Insight
Fag:
Immunology
Transplantation
Online adgang:https://doi.org/10.1172/jci.insight.154440
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