<i>Ramulus Mori</i> (Sangzhi) Alkaloids Improve Pancreatic β-Cell Function Through Gut Microbial and Intra-Islet 2-Methoxyestradiol Biosynthesis

<b>Background</b>: <i>Ramulus Mori</i> (Sangzhi) Alkaloids (SZ-A) are natural hypoglycemic compounds known to enhance insulin secretion. Given the emerging role of the gut microbiota in regulating β-cell function, in this study, we aimed to investigate whether SZ-A exert their beneficial effects thr...

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Autori principali:	Nan Wu, Lusi Lu, Yiming Liu, Sunyue He, Chunyi Xu, Ying Wu, Yuchen Zhao, Xihua Lin, Wenjing Zhang, Jiaqiang Zhou
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-08-01
Serie:	Biomedicines
Soggetti:	<i>Ramulus Mori</i> (Sangzhi) alkaloids gut microbiota metabolites β-cell function 2-methoxyestradiol
Accesso online:	https://www.mdpi.com/2227-9059/13/8/2013
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