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The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency

Abstract Background Small nucleolar RNA host gene 3 (Snhg3) is a long non-coding RNA (lncRNA) that was shown to participate in the tumorigenesis of certain cancers. However, little is known about its role in embryonic stem cells (ESCs). Methods Here, we investigated the role of Snhg3 in mouse ESCs (...

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Principais autores: Weisi Lu, Jianping Yu, Fengtao Shi, Jianing Zhang, Rui Huang, Shanshan Yin, Zhou Songyang, Junjiu Huang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-05-01
Serier:Stem Cell Research & Therapy
Fag:
lncRNA
Snhg3
mESCs
Self-renewal
Pluripotency
Online adgang:http://link.springer.com/article/10.1186/s13287-019-1270-5
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