Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining

Abstract Background Induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) share many common features, including similar morphology, gene expression and in vitro differentiation profiles. However, genomic stability is much lower in iPSCs than in ESCs. In the current study, we examine...

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Autori principali:	Minjie Zhang, Liu Wang, Ke An, Jun Cai, Guochao Li, Caiyun Yang, Huixian Liu, Fengxia Du, Xiao Han, Zilong Zhang, Zitong Zhao, Duanqing Pei, Yuan Long, Xin Xie, Qi Zhou, Yingli Sun
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2018-07-01
Serie:	Cancer Communications
Soggetti:	Genomic stability DNA damage repair iPSCs ESCs
Accesso online:	http://link.springer.com/article/10.1186/s40880-018-0313-0
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