Assessing the association of leukocyte telomere length with ankylosing spondylitis and rheumatoid arthritis: A bidirectional Mendelian randomization study

BackgroundTelomere length shortening can cause senescence and apoptosis in various immune cells, resulting in immune destabilization and ageing of the organism. In this study, we aimed to systematically assess the causal relationship of leukocyte telomere length (LTL) with ankylosing spondylitis (AS...

Полное описание

Библиографические подробности

Главные авторы:	Donglei Wei, Yage Jiang, Jianwen Cheng, Hui Wang, Ke Sha, Jinmin Zhao
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-03-01
Серии:	Frontiers in Immunology
Предметы:	leukocyte telomere length ankylosing spondylitis rheumatoid arthritis Mendelian randomization single nucleotide polymorphism
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1023991/full
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